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Salvinorin B methoxymethyl ether

$120.00$750.00

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Overview of Salvinorin B Methoxymethyl Ether in the USA

Salvinorin B methoxymethyl ether in the USA is a synthetic compound derived from a naturally  substance found in the leaves of the Divinorum plant. This specialized compound is primarily utilized for scientific research to explore its unique pharmacological properties. One key characteristic of Salvinorin B is its extended duration of effect, typically lasting between 2 to 3 hours, which is significantly longer than that of Salvinorin A. This extended duration positions of this drugs as a compelling subject for further investigation within the field of psychoactive substances.

Availability of Salvinorin B Methoxymethyl Ether in the USA

In the USA, Salvinorin B methoxymethyl ether is available for purchase, with various online platforms offering it under research-oriented frameworks. Notably, Alliance Easy Script is one such platform that provides this compound at competitive prices. The ordering process is straightforward, often not requiring a prescription, thereby enhancing accessibility for researchers and interested individuals exploring its scientific and therapeutic potential.

Biological Activity and Research Implications

Salvinorin B methoxymethyl ether is classified as a neoclerodane diterpene, recognized for its selective agonistic activity at the kappa-opioid receptor (KOR) in the USA. This property has attracted significant attention in pharmacological research due to its distinctive effects and potential therapeutic applications. Research on the biological activity of Salvinorin B reveals its mechanisms of action and pharmacological effects, paving the way for future studies that could uncover additional therapeutic uses.

Chemical Structure and Properties

The chemical identity of Salvinorin B is defined by the following:

Chemical Formula: C21H26O7
Molecular Weight: 390.44 g/mol

As a metabolite of Salvinorin B methoxymethyl, this compound exhibits potent psychoactive effects in the USA. Unlike Salvinorin A, Salvinorin B does not have significant analgesic properties but functions as a selective KOR DREADD (Designer Receptor Exclusively Activated by Designer Drugs) activator, showcasing an EC50 value of 11.8 nM. Its principal mechanism is centered around the activation of the kappa-opioid receptor, which leads to neuronal hyperpolarization and can influence behaviors such as locomotion and feeding in KORD-expressing mouse models. The stimulation of KOR is linked to various physiological responses, including pain perception modulation and stress response regulation.

In summary, it represents a significant area of interest in pharmacology and psychoactive research in the USA, offering insights that may contribute to future therapeutic developments.

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