Overview of 3-CMC 3-Chloromethcathinone (Clophedrone) in the USA
Chemical Identification and Properties
3-CMC , commonly known as Clophedrone (3-Chloromethcathinone), is a synthetic stimulant that belongs to the cathinone class of chemicals in the USA. It exhibits a structural resemblance to cathinone, a natural stimulant derived from the khat plant. 3-Chloromethcathinone Clophedrone is a laboratory-modified variation of a naturally occurring stimulant, designed specifically for certain research applications in the USA. These modifications change its properties and effects, thereby making it an interesting subject for pharmacological research.
Availability of 3-CMC in the USA
In the USA, 3-CMC Clophedrone is available in its crystal form as a designer drug and is structurally related to bupropion. Despite their similarities, the pharmacological effects of these substances can vary significantly. The chemical formula for 3-Chloromethcathinone is C10H12ClNO, with a molar mass of 197.66 g·mol⁻¹. Since October 2015, it has been classified as a controlled substance under US law. Its structure is characterized by a ketone substitution on the beta carbon of the amphetamine skeleton, which classifies it as a β-keto-amphetamine. Furthermore, Clophedrone has two methyl substitutions in its structure—one on the phenyl ring and another on the nitrogen group—similar to mephedrone, though differing in the position of one methyl group.
In Canada, Clophedrone is restricted for research purposes only and is prohibited for use in diagnostics, food, drugs, medicinal devices, and cosmetics intended for humans and animals. This requires individuals interested in acquiring the substance to be at least 18 years old and capable of safely handling research chemicals within a well-ventilated environment.
Potential Effects and Applications
As a synthetic research chemical, 3-CMC (Clophedrone) holds considerable potential for various scientific and industrial applications in the USA. It is categorized as a substituted cathinone, a category known for its psychoactive properties, including entactogenic effects that enhance emotional connections and empathy. Additionally, it exhibits stimulant effects that can increase alertness and energy levels.
Moreover, the chemical structure of Clophedrone bears a close resemblance to mephedrone, a well-known member of the cathinone family in the USA. The primary distinction lies in its molecular structure, where a chlorine atom replaces the methyl group typically found in the nitrogen atom of mephedrone. This structural modification may influence its pharmacological effects and potential applications.
Lastly, the formal designation of 3-CMC (Clophedrone) 3-Chloromethcathinone is 1-(3-chlorophenyl)-2-(methylamino)-1-propanone, highlighting its chemical composition in the USA. It exists as hydrochloride in a stable salt form, with the molecular formula C10H12ClNO • HCl, indicating the presence of carbon, hydrogen, nitrogen, oxygen, and chlorine elements.
